Restoring function to the injured human spinal cord /
[Book]
Richard Ben Borgens
xvi, 161 pages :
illustrations (some color) ;
24 cm
Advances in anatomy, embryology, and cell biology,
v. 171
0301-5556 ;
Includes bibliographical references (pages 141-155) and index
Brief primer on spinal cord injury -- Behavioral catastrophe is rooted in injury to white matter -- Scar as a barrier to regeneration -- Treating the acute and chronic injury: historical perspective -- Concerning behavioral models for spinal cord injury in animals -- Axonal regeneration -- Treatment possibilities of the new biology -- Biologically produced electrical fields: physiology spoken here -- Endogenous voltages and the reaction of the neuron to injury -- Responses of isolated nerve fibers in culture to applied DC voltages -- Enhancing spinal cord regeneration in situ with applied electric fields -- Recovery of the CTM reflux in spinal injured guinea pigs after exposure to applied extracellular voltages -- From a laboratory tool to a clinical application -- Naturally occurring spinal injury in the dog as a model for man -- Sealing the breach in cell membranes with hydrophilic polymers -- Recovery of behavioral and physiological function in vivo -- PEG application in clinical cases of canine paraplegia -- Conclusion
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Provides a general understanding of the biology of spinal cord injury (SCI) in animal models and their relationship to naturally occurring injury in man, and secondly reviews novel means to induce functional recovery from spinal cord injury based on developmental biophysics and physiology
Biophysics
Physiology, Comparative
Spinal cord-- Wounds and injuries-- Patients-- Rehabilitation