composition, complexity, dynamics, and biological implications /
Esteban Domingo
xvi, 412 pages :
illustrations (chiefly color) ;
24 cm
Includes bibliographical references and indexes
Introduction to virus origins and their role in biological evolution -- Molecular basis of genetic variation of viruses : error-prone replication -- Darwinian principles acting on highly mutable viruses -- Interaction of virus populations with their hosts -- Viral fitness as a measure of adaptation -- Virus population dynamics examined with experimental model systems -- Long-term virus evolution in nature -- Quasispecies dynamics in disease prevention and control -- Trends in antiviral strategies -- Collective population effects in nonviral systems