Alcohol Metabolism, Alcohol Intolerance, and Alcoholism :
[Book]
Biochemical and Pharmacogenetic Approaches
by Dharam P. Agarwal, H. Werner Goedde.
Berlin, Heidelberg
Springer Berlin Heidelberg
1990
(x, 184 pages 46 illustrations, 1 illustration in color.)
1 Introduction --;2 Alcohol Metabolism: Biochemistry and Genetic Variations --;2.1Absorption, Body Distribution, and Elimination of Ethanol --;2.2 Biochemical Pathways of Ethanol Degradation --;3 Alcohol-Metabolizing Enzymes and Acute Reactions to Alcohol --;3.1Ethanol- and Acetaldehyde-Mediated Acute Response to Alcohol --;3.2 Ethnic Differences in Acute Response to Alcohol 53 --;3.3 Mechanism of Alcohol Sensitivity --;3.4 Racial-Ethnic Patterns of Alcohol Abuse and Alcoholism --;4Biochemical Aspects of Alcoholism --;4.1 Alcohol-Related Metabolic Derangements --;4.2 Metabolic Changes --;4.3Changes in Alcohol-Metabolizing Enzymes in Alcohol-Related Disorders --;4.4Biochemical Markers of Alcohol Abuse and Alcoholism --;5Neuropsychopharmacology of Alcoholism --;5.1 Alcohol Effects in the CNS --;5.2Addiction, Tolerance, and Dependence --;5.3Metabolic Factors --;6Genetic Factors in Alcoholism --;6.1 Ethnic and Cultural Variables --;6.2 Familial and Nonfamilial Alcoholism --;6.3 Genetic Contributions --;6.4Genetic and Environmental Interactions in Alcoholism --;6.5Biological Mediators of Alcoholism --;7Experimental Section --;7.1Subjects and Materials --;7.2Methods --;References 145 --;Subject Index 179.
Alcohol abuse, alcohol intolerance, alcohol dependence and other alcohol-related disabilities are some of the most challenging public health problems facing our modern-day society.