عنوان

Thiol metabolism and redox regulation of cellular functions /

0585458707

1601294727

6610505675

9780585458700

9781601294722

9786610505678

1586032828

427490542X

9781586032821

9784274905421

b709005

Thiol metabolism and redox regulation of cellular functions /

[Book]

[edited by] Alfonso Pompella, Gabor Banhegyi, Maria Wellman-Rousseau.

Washington, DC :

IOS Press,

©2002.

1 online resource (xii, 350 pages) :

illustrations

NATO science series. Series I, Life and behavioural sciences,

v. 347

1566-7693 ;

"Proceedings of the NATO Advanced Research Workshop on Thiol Metabolism and Redox Regulation of Cellular Functions, 10-13 April 2002, Pisa, Italy"--Title page verso.

"Published in cooperation with NATO Scientific Affairs Division."

Includes bibliographical references and index.

Oxidative signaling and glutathione synthesis -- Cell survival and changes in gene expression in cells unable to synthesize glutathione -- Role of glutathione in the regulation of liver metabolism -- Glutathione transport in the endo/sarcoplasmic reticulum -- Role of ascorbate in oxidative protein folding -- Cytophotometric investigations on oscillating thiol-disulfide equilibria and oxidized protein sulfur -- Protection by pantothenic acid against apoptosis and cell damage by oxygen free radicals -- the role of glutathione -- Thiols as major determinants of the total antioxidant capacity -- Enzymes of the thio9l-dependent hydroperoxide metabolism in pathogens as potential drug targets -- Is there a role of glutathione peroxidases in signaling and differentiation? -- Multidrug resistance-associated proteins: export pumps for conjugates with glutathione, glucuronate or sulfate -- Detoxification of eletrophilic compounds by glutathione s-transferase catalysis: determinants of individual response to chemical carcinogens and chemotherapeutic drugs? -- Transcriptional regulation of glutathione s-transferase P1-1 in human leukemia -- Mechanism of [gamma]-glutamyltranspeptidase folding and activation in the endoplasmic reticulum.

The role of [gamma]-glutamyl transpeptidase in the biosynthesis of glutathione -- Role of [gamma]-glutamyltransferase in the homeostasis of glutathione during oxidative and nitrosative stress -- The importance of gamma-glutamyl transferase in lung glutathione homeostasis and antioxidant defense -- The role of gamma-glutamyltranspeptidase in the metabolism and cytotoxicity of 4-hydroxynonenal-glutathione conjugate: evidence and hypothesis -- [gamma]-glutamyltransferase-dependent prooxidant reactions: a factor in multiple processes -- Serum gamma-glutamyl transpeptidase: a prognostic marker in cardiovascular diseases -- Lipoic acid: a multifunctional antioxidant -- Is glutathione an important neuroprotective effector molecule against amyloid beta toxicity? -- Antioxidants in cancer therapy: is there a rationale to recommend antioxidants during cancer therapy? -- Disulfide exchange in CD4 -- Redox regulation in protein folding and chaperone function -- Reduction of the endoplasmic reticulum accompanies the oxidative damage of diabetes mellitus -- Analytical developments in the assay of intra- and extracellular GSH homeostasis -- Signalling potential and protein modifying ability of physiological thiols -- Redox signaling and the map kinase pathways -- Redox regulation of mitochondrial permeability transition: contrasting effects of lipoic acid and its positively charged analog LA-plus -- Redox state of glutathione and.

0

0

This volume contains contributions by some of the leading scientists in the field of thiol oxidation/reduction (redox) biochemistry. It is focused on the biological/pathophysiological implications of newly-discovered functions of cellular thiols, such as glutathione in the first place.

Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.

Thiol metabolism and redox regulation of cellular functions.

Antioxidants, Congresses.

Cell respiration, Congresses.

Glutathione-- Physiological effect, Congresses.

Oxidation-reduction reaction, Congresses.

Thiols-- Physiological effect, Congresses.

Cell Physiological Phenomena.

gamma-Glutamyltransferase.

Glutathione.

Oxidation-Reduction.

Antioxidants.

Cell respiration.

Glutathione-- Physiological effect.

MEDICAL-- Health Risk Assessment.

Oxidation-reduction reaction.

Thiols-- Physiological effect.

MED-- 037000

Bánhegyi, Gábor.

Pompella, Alfonso.

Wellman-Rousseau, Maria.

NATO Advanced Research Workshop on Thiol Metabolism and Redox Regulation of Cellular Functions(2002 :, Pisa, Italy)

20201207235308.0

pn

[Book]

Y