Front Cover; Inside Cover; Table of Contents; Editors / Contributors; Preface; Chapter 1Targeting and Activation of Peptide Hormones in the Secretory Pathway; Chapter 2 The Mechanism of Sorting Proopiomelanocortin to Secretory Granules and Its Processing by Aspartic and PC Enzymes; Chapter 3 The Mammalian Precursor Convertases:; Chapter 4 The Neuroendocrine Prohormone Convertases PC1, PC2 and PC5; Chapter 5 'Prohormone Thiol Protease' (PTP), a Novel Cysteine Protease for Proenkephalin and Prohormone Processing.
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This text is designed to provide the reader with an understanding of current knowledge concerning proteases involved in prohormone processing, and cellular aspects that must be considered for proper processing, storage, and secretion of bioactive peptides.
Proteolytic and cellular mechanisms in prohormone and proprotein processing.
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Peptide hormones-- Metabolism.
Peptide hormones-- Physiological transport.
Post-translational modifications.
Protein precursors.
Proteolytic enzymes.
Peptide Hydrolases-- metabolism.
Protein Precursors-- metabolism.
Protein Processing, Post-Translational-- physiology.
Proteins-- metabolism.
Aufsatzsammlung
Endopeptidasen
Enzymatische Regulation
Enzymkatalyse
Modifications post-traductionnelles des protéines-- physiologie.