Demographics and Quality of Life Effects of Normobaric Oxygen on Cohort of Patients with Retinal Vein Occlusions
نام عام مواد
[Thesis]
نام نخستين پديدآور
Minturn, Robert J.
نام ساير پديدآوران
Arroyo, Jorge
وضعیت نشر و پخش و غیره
نام ناشر، پخش کننده و غيره
Boston University
تاریخ نشرو بخش و غیره
2019
مشخصات ظاهری
نام خاص و کميت اثر
56
یادداشتهای مربوط به پایان نامه ها
جزئيات پايان نامه و نوع درجه آن
M.S.
کسي که مدرک را اعطا کرده
Boston University
امتياز متن
2019
یادداشتهای مربوط به خلاصه یا چکیده
متن يادداشت
Purpose: This study examined the effects of normobaric oxygen in patients diagnosed with either a Central Retinal Vein Occlusion (CRVO) or Branched Retinal Vein Occlusion (BRVO) who had previously undergone treatment via Anti-VEGF or PRP treatment. The investigation looked into the changes in Macular Thickness (MT) and Visual Acuity (VA). Methods: This pilot study analyzed patient data from Beth Israel Deaconess Medical Center (Boston, MA) that had been diagnosed with Retinal Vein Occlusions. The patients were brought in and given 3 hours of normobaric oxygen via an oxygen concentrator with imaging and vision checked both before and after the therapy. Results: Eighty-eight percent of our patients in this pilot study saw a decrease in macular thickness after 3-hour oxygen therapy. The mean change in Maximal Macular Thickness was a decrease of 7.1% which was statistically significant when compared to healthy eyes (p<0.001). Additionally, 44% of patients saw an increase in visual acuity, the primary measure of vision. Visual acuity showed a statistically significant change when compared to changes in healthy eyes (p=0.015). No statistical significance was found in the testing of contrast sensitivity nor intraocular pressure. Conclusion: Our study showed improvement in central macular thickness and quality of life for individuals using noninvasive normobaric hyperoxia as a treatment for retinal vein occlusions. However, further research is needed to improve the impact of the study and a full randomized control trial should be implemented to further understand the potential impacts of a noninvasive normobaric hyperoxia treatment as a means to alleviate symptoms in retinal vein occlusions. In addition, in the future oxygen supplementation in conjunction with periodic injections of Anti-VEGF could be investigated as a treatment regimen with potential benefits beyond individual therapy.
موضوع (اسم عام یاعبارت اسمی عام)
موضوع مستند نشده
Biochemistry
موضوع مستند نشده
Medicine
موضوع مستند نشده
Ophthalmology
موضوع مستند نشده
Physiology
موضوع مستند نشده
Public health
نام شخص به منزله سر شناسه - (مسئولیت معنوی درجه اول )