challenges and practices for the pharmaceutical and fine chemical industries /
First Statement of Responsibility
edited by Peter J. Dunn, Pfizer Green Chemistry Lead, Sandwich, Kent, United Kingdom, K.K. (Mimi) Hii, Imperial College London, South Kensington, London, United Kingdom, Michael J. Krische, University of Texas at Austin, Austin, Texas, United States of America, Michael T. Williams, CMC Consultant, Deal, Kent, United Kingdom.
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
1 online resource (xv, 421 pages) :
Other Physical Details
illustrations.
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index.
CONTENTS NOTE
Text of Note
Catalytic Reduction of Amides Avoiding LiAlH OR BH / Deborah L Dodds, David J Cole-Hamilton -- Hydrogenation of Esters / Lionel A Saudan -- Synthesis of Chiral Amines Using Transaminases / Nicholas J Turner, Matthew D Truppo -- Development of A Sitagliptin Transaminase / Jacob M Janey -- Direct Amide Formation Avoiding Poor Atom Economy Reagents / Benjamin M Monks, Andrew Whiting -- Industrial Applications of Boric Acid And Boronic Acid-Catalyzed Direct Amidation Reactions / Joanne E Anderson, Jannine Cobb, Roman Davis, Peter J Dunn, Russ N Fitzgerald, Alan J Pettman -- OH Activation for Nucleophilic Substitution / Jonathan MJ Williams -- Application of A Redox-Neutral Alcohol Amination in The Kilogram-Scale Synthesis of A GlyT1 Inhibitor / Martin A Berliner -- Olefin Metathesis: From Academic Concepts to Commercial Catalysts / Justyna Czaban, Christian Torborg, Karol Grela -- Challenge and Opportunity in Scaling-Up Metathesis Reaction: Synthesis of Ciluprevir (BILN 2061) / Nathan Yee, Xudong Wei, Chris Senanayake -- C-H Activation of Heteroaromatics / Koji Hirano, Masahiro Miura -- The Discovery of A New Pd/Cu Catalytic System For C-H Arylation and Its Applications in A Pharmaceutical Process / Jinkun Huang, Xiang Wang, Johann Chan -- Diarylprolinol Silyl Ethers: Development and Application As Organocatalysts / Hiroaki Gotoh, Yujiro Hayashi -- Organocatalysis for Asymmetric Synthesis: From Lab To Factory / Feng Xu -- Catalytic Variants of Phosphine Oxide-Mediated Organic Transformations / Stephen P Marsden -- Formation of C-C BONDS via Catalytic Hydrogenation and Transfer Hydrogenation / Joseph Moran, Michael J Krische.