عنوان

Cholesterol modulation of protein function :

(Number (ISBN

3030042782

(Number (ISBN

3030042790

(Number (ISBN

9783030042783

(Number (ISBN

9783030042790

Erroneous ISBN

3030042774

Erroneous ISBN

9783030042776

Title Proper

Cholesterol modulation of protein function :

General Material Designation

[Book]

Other Title Information

sterol specificity and indirect mechanisms /

First Statement of Responsibility

Avia Rosenhouse-Dantsker, Anna N. Bukiya, editors.

Place of Publication, Distribution, etc.

Cham, Switzerland :

Name of Publisher, Distributor, etc.

Springer,

Date of Publication, Distribution, etc.

2019.

Specific Material Designation and Extent of Item

1 online resource (x, 197 pages) :

Other Physical Details

illustrations (some color)

Series Title

Advances in experimental medicine and biology,

Volume Designation

volume 1115

ISSN of Series

2214-8019 ;

Text of Note

Includes bibliographical references and index.

Text of Note

Sterol specificity in modulating protein function. Chirality effect on cholesterol modulation of protein function / Jitendra D. Belani -- A critical analysis of molecular mechanisms underlying membrane cholesterol sensitivity of GPCRs / Md. Jafurulla, G. Aditya Kumar, Bhagyashree D. Rao, Amitabha Chattopadhyay -- Regulation of BK channel activity by cholesterol and its derivatives / Anna N. Bukiya, Alex M. Dopico -- Chiral specificity of cholesterol orientation within cholesterol binding sites in inwardly rectifying K+ channels / Nicolas Barbera, Irena Levitan -- Indirect modulation of protein function by cholesterol. Cholesterol effects on the physical properties of lipid membranes viewed by solid-state NMR spectroscopy / Trivikram R. Molugu, Michael F. Brown -- Effect of cholesterol on the dipole potential of lipid membranes / Ronald J. Clarke -- Mass spectrometry imaging of cholesterol / Stephanie M. Cologna -- Cholesterol-dependent gating effects on ion channels / Qiu-Xing Jiang.

0

Text of Note

"In this book, renowned scientists describe the role of steroid chirality and modification of lipid membrane physical properties in the modulation of G protein-coupled receptors and ion channels. The application of commonly-used technical approaches such as mass spectrometry and nucleic magnetic resonance transfer spectroscopy for studies on cholesterol distribution and alteration of lipid bilayer characteristics is also discussed. This book offers comprehensive insights into the current understanding of cholesterol-driven modulation of protein function via mechanisms that extend beyond lipid-protein direct interactions. In the first part, the chapters introduce the reader to the use of the chemical derivatives of cholesterol as a valuable laboratory tool in the studies of cholesterol-driven modulation of protein function. In the second part, examples of cholesterol-induced changes in membrane physical characteristics are presented and discussed in light of their multifaceted contribution to the effect of cholesterol on protein function. The book will be of interest to undergraduate and graduate students as well as basic science and medical researchers with a keen interest in the biophysical properties of cholesterol and physiological consequences of cholesterol presence in biological systems"--Publisher's description.

Source for Acquisition/Subscription Address

Springer Nature

Stock Number

com.springer.onix.9783030042783

International Standard Book Number

9783030042776

International Standard Book Number

9783030042790

Cholesterol.

Proteins.

Cholesterol-- metabolism.

Cholesterol-- physiology.

Ion Channel Gating-- physiology.

Ion Channels-- physiology.

Membrane Lipids-- physiology.

Receptors, G-Protein-Coupled-- physiology.

Cholesterol.

Proteins.

SCIENCE-- Life Sciences-- Biochemistry.

PSB

PSBC

SCI-- 007000

Number

Edition

Class number

Class number

Bukiya, Anna N.

Rosenhouse-Dantsker, Avia

Date of Transaction

20200823080409.0

Cataloguing Rules (Descriptive Conventions))

pn

Electronic name

[Book]

Y