عنوان

Bioengineering and molecular biology of plant pathways /

(Number (ISBN

0080449727

(Number (ISBN

0080556965

(Number (ISBN

1281144703

(Number (ISBN

6611144706

(Number (ISBN

9780080449722

(Number (ISBN

9780080556963

(Number (ISBN

9781281144706

(Number (ISBN

9786611144708

Erroneous ISBN

0080449727

Erroneous ISBN

9780080449722

Number

b723499

Title Proper

Bioengineering and molecular biology of plant pathways /

General Material Designation

[Book]

First Statement of Responsibility

edited by Hans Bohnert, Henry Nguyen, Norman G. Lewis.

Place of Publication, Distribution, etc.

Boston :

Name of Publisher, Distributor, etc.

Pergamon,

Date of Publication, Distribution, etc.

2008.

Specific Material Designation and Extent of Item

1 online resource (xxiii, 455, 28 pages) :

Other Physical Details

illustrations.

Series Title

Advances in plant biochemistry and molecular biology ;

Volume Designation

v. 1

Text of Note

Includes bibliographical references and index.

Text of Note

Front Cover; Bioengineering and Molecular Biology of Plant Pathways; Copyright Page; Dedication Page; Contents; Contributors; Introduction to the Series and Acknowledgements; Preface to Volume 1; Prologue; Chapter 1: Metabolic Organization in Plants: A Challenge for the Metabolic Engineer; 1. Introduction; 2. Plant Metabolic Networks and Their Organization; 3. Tools for Analyzing Network Structure and Performance; 3.1. Constraints-based network analysis; 3.2. Metabolic flux analysis; 3.3. Kinetic modeling; 3.4. Metabolic control analysis; 4. Integration of Plant Metabolism

Text of Note

2.2. Genomic analysis suggests most enzymes evolve from preexisting enzymes2.3. Evolution of a new enzymatic activity in nature; 2.4. The natural evolution process initially produces poor enzymes; 2.5. Sequence space and fitness landscapes; 3. Practical Considerations for Engineering Enzymes; 3.1. Identifying appropriate starting enzyme(s); 3.2. Ways of introducing variability into genes; 3.3. Choice of expression system; 3.4. Identifying improved variants; 3.5. Recombination and/or introduction of subsequent mutations; 3.6. Structure-based rational design

Text of Note

2.3. Glutamate dehydrogenase: An enzyme with controversial functions in plants2.4. The network of amide amino acids metabolism is regulated in concert by developmental, physiological, environmental, metabolic, and stress-derived signals; 3. The Aspartate Family Pathway that is Responsible for Synthesis of the Essential Amino Acids Lysine, Threonine, Methionine, and Isoleucine; 3.1. The aspartate family pathway is regulated by several feedback inhibition loops; 3.2. Metabolic fluxes of the aspartate family pathway are regulated by developmental, physiological, and environmental signals

Text of Note

4. Opportunities for Plant Improvement Through Engineered Enzymes and Proteins4.1. Challenges for engineering plant enzymes and pathways; 5. Summary; Acknowledgements; References; Chapter 3: Genetic Engineering of Amino Acid Metabolism in Plants; 1. Introduction; 2. Glutamine, Glutamate, Aspartate, and Asparagine are Central Regulators of Nitrogen Assimilation, Metabolism, and Transport; 2.1. GS: A highly regulated, multifunctional gene family; 2.2. Role of the ferredoxin- and NADH-dependent GOGAT isozymes in plant glutamate biosynthesis

Text of Note

4.1. Relationship between enzyme properties and network fluxes4.2. Limitations on metabolic compensation within a network; 4.3. Impact of physiological conditions on network performance; 4.4. Network adjustments through alternative pathways; 4.5. Propagation of metabolic perturbations through networks; 4.6. Enzyme-specific responses within networks; 4.7. Impact of metabolic change on network structure; 5. Summary; Acknowledgements; References; Chapter 2: Enzyme Engineering; 1. Introduction; 2. Theoretical Considerations; 2.1. Enzyme architecture is conserved

0

8

8

8

8

Text of Note

The increased knowledge about the structure of genomes in a number of species, about the complexity of transcriptomes, and the rapid growth in knowledge about mutant phenotypes have set off the large scale use of transgenes to answer basic biological questions, and to generate new crops and novel products. This volume includes twelve chapters, which to variable degrees describe the use of transgenic plants to explore possibilities and approaches for the modification of plant metabolism, adaptation or development. The interests of the authors range from tool development, to basic biochemical know-how about the engineering of enzymes, to exploring avenues for the modification of complex multigenic pathways, and include several examples for the engineering of specific pathways in different organs and developmental stages. * Prologue by Paul K. Stumpf and Eric E. Conn * Incorporates new concepts and insights in plant biochemistry and biology * Provides a conceptual framework regarding the challenges faced in engineering pathways * Discusses potential in engineering of metabolic end-products that are of vast economical importance including genetic engineering of cellulose, seed storage proteins, and edible and industrial oils.

Source for Acquisition/Subscription Address

Elsevier Science & Technology

Source for Acquisition/Subscription Address

OverDrive, Inc.

Stock Number

98514:98517

Stock Number

A7207E02-B4AD-4F57-B0DA-661778405E8E

Title

Bioengineering and molecular biology of plant pathways.

International Standard Book Number

0080449727

Botanical chemistry.

Plant biotechnology.

Plant molecular biology.

Botanical chemistry.

Plant biotechnology.

Plant molecular biology.

SCIENCE-- Life Sciences-- Biochemistry.

SCI-- 007000

Number

Edition

Class number

Book number

Bohnert, Hans J.

Lewis, Norman G.,1949-

Nguyen, Henry T.

Date of Transaction

20201209095519.0

Cataloguing Rules (Descriptive Conventions))

pn

Electronic name

[Book]

Y