عنوان
پدید آورنده
موضوع
رده
کتابخانه
محل استقرار
NATIONAL BIBLIOGRAPHY NUMBER
Number
TL53987
LANGUAGE OF THE ITEM
.Language of Text, Soundtrack etc
انگلیسی
TITLE AND STATEMENT OF RESPONSIBILITY
Title Proper
Development and In-Silico Evaluation of a Closed-Loop Fluid Resuscitation Control Algorithm with Mean Arterial Pressure Feedback
General Material Designation
[Thesis]
First Statement of Responsibility
Alsalti, Mohammad Salahaldeen Ahmad
Subsequent Statement of Responsibility
Hahn, Jin-Oh
.PUBLICATION, DISTRIBUTION, ETC
Name of Publisher, Distributor, etc.
University of Maryland, College Park
Date of Publication, Distribution, etc.
2020
GENERAL NOTES
Text of Note
86 p.
DISSERTATION (THESIS) NOTE
Dissertation or thesis details and type of degree
M.S.
Body granting the degree
University of Maryland, College Park
Text preceding or following the note
2020
SUMMARY OR ABSTRACT
Text of Note
In this thesis, a model-based closed-loop fluid resuscitation controller using mean arterial pressure (MAP) feedback is designed and later evaluated on an in-silico testbed. The controller is based on a subject specific model of blood volume and MAP response to fluid infusion. This simple hemodynamic model is described using five parameters only. The model was able to reproduce blood volume and blood pressure response to fluid infusion using an experimental dataset collected from 23 sheep and is therefore suitable to use for control design purposes. A model-reference adaptive control scheme was chosen to account for inter-subject variability captured in the parametric uncertainties of the underlying physiological model. Three versions of the control algorithm were studied under different measurement availability scenarios. In-silico evaluation of the three controllers was done using a comprehensive cardiovascular physiology model on a cohort of 100 virtually generated patients. Results clearly show that a tradeoff exists between tracking and estimation performance depending on measurement availability.
UNCONTROLLED SUBJECT TERMS
Subject Term
Biomedical engineering
Subject Term
Fluid mechanics
Subject Term
Mechanical engineering
PERSONAL NAME - PRIMARY RESPONSIBILITY
Alsalti, Mohammad Salahaldeen Ahmad
PERSONAL NAME - SECONDARY RESPONSIBILITY
Hahn, Jin-Oh
CORPORATE BODY NAME - SECONDARY RESPONSIBILITY
University of Maryland, College Park
ELECTRONIC LOCATION AND ACCESS
Electronic name
مطالعه متن کتاب p
[Thesis]
276903
a
Y
