عنوان

Quantitative Aspects of Allosteric Mechanisms

شابک

3642812317

شابک

3642812333

شابک

9783642812316

شابک

9783642812330

شماره

b551749

عنوان اصلي

Quantitative Aspects of Allosteric Mechanisms

نام عام مواد

[Book]

نام نخستين پديدآور

by Alexander Levitzki.

محل نشرو پخش و غیره

Berlin, Heidelberg

نام ناشر، پخش کننده و غيره

Springer Berlin Heidelberg

تاریخ نشرو بخش و غیره

1978

عنوان فروست

Molecular biology, biochemistry, and biophysics, 28.

متن يادداشت

1 Basic Concepts of Allosteric Control --;2 The Structure of Multisubunit Proteins --;I. General Principles --;II. Other Types of Protein Assemblies --;3 Cooperativity in Multisubunit Proteins --;The Basic Concepts --;I. The Hill Equation --;II. The General Adair Equation --;III. The Statistical Correction --;IV. The Hill Coefficient in Terms of Intrinsic Ligand Affinities --;V. The Hill Coefficient at 50% Ligand Saturation --;VI. The Maximal Hill Coefficient --;VII. The Limiting Values of the Hill Slope --;VIII. The Allosteric Dimer --;IX. The Multi-Dimer Case --;X. The Allosteric Tetramer --;XI. The General Tetrameric Case --;4 The Energy of Subunit Interactions --;I. Determination of Intersubunit Interaction Energy --;II. The Hill Coefficient and the Intersubunit Interaction Energy --;III. The Meaning of Intersubunit Energy of Interaction --;5 Molecular Models for Cooperativity and Allosteric Interactions --;I. Introduction --;II. The Monod-Wyman-Changeux (MWC) Concerted Model --;III. The Koshland-Némethy-Filmer (KNF) Sequential Model --;IV. The Conformational State of the Protein --;V. Comparison Between the KNF Model and the MWC Model --;6 Special Types of Cooperative Systems --;I. Cooperativity Resulting from Ligand-Coupled Protein Association or Dissociation --;II, Negative Cooperativity --;III. Protein Association and Dissociation Coupled to Ligand Binding --;1, Dimerization Coupled to Ligand Binding --;2. Monomer Multimer Equilibrium Coupled to Ligand Binding --;References.

متن يادداشت

Special emphasis has been given to the analysis of the Hill coefficient and its meaning both in thermodynamic terms and in terms of the two allosteric models: the concerted model of Monod, Wyman and Changeux and the sequential model of Koshland, Nemethy and Filmer.

موضوع مستند نشده

Allosteric Regulation.

موضوع مستند نشده

Life sciences.

موضوع مستند نشده

Medicine.

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

by Alexander Levitzki.

مستند نام اشخاص تاييد نشده

Alexander Levitzki

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y