عنوان

A case of de novo palmoplantar psoriasis with psoriatic arthritis and autoimmune hypothyroidism after receiving nivolumab therapy

شماره

LA12n4m6pm

زبان متن نوشتاري يا گفتاري و مانند آن

انگلیسی

عنوان اصلي

A case of de novo palmoplantar psoriasis with psoriatic arthritis and autoimmune hypothyroidism after receiving nivolumab therapy

نام عام مواد

[Article]

نام نخستين پديدآور

Elosua-González, Marta; Pampín-Franco, Ana; Mazzucchelli-Esteban, Ramón; Mielgo-Rubio, Xabier; Rodriguez-Vásquez, Ximena; García-Zamora, Elena; López-Estebaranz, Jose Luis

متن يادداشت

Nivolumab, a monoclonal antibody against the programmed cell death protein 1 (PD-1), has shown promising results in patients with advanced malignancies, including melanoma, lung cancer, and renal cancer. Immune-related adverse events (irAEs) have been reported, including both organ-specific toxicities and skin toxicities. Herein, we report a case of predominantly palmoplantar psoriasis with severe nail involvement, psoriatic arthritis, and autoimmune hypothyroidism after receiving nivolumab treatment for lung cancer. We also summarize the case reports that have been published previously. The knowledge of these irAEs in patients undergoing anti-PD1 therapy is important since it will enable earlier recognition and appropriate management, with the aim of maintaining effective dose without disruption.

تاريخ نشر

2017

عنوان

Dermatology Online Journal

شماره جلد

23/8

عنصر شناسه اي

Elosua-González, Marta; Pampín-Franco, Ana; Mazzucchelli-Esteban, Ramón; Mielgo-Rubio, Xabier; Rodriguez-Vásquez, Ximena; García-Zamora, Elena; López-Estebaranz, Jose Luis

نام الکترونيکي

نوع ماده

[Article]

کد کاربرگه

275578

سطح دسترسي

a

تكميل شده

Y