عنوان
پدید آورنده
موضوع
رده
کتابخانه
محل استقرار
شماره کتابشناسی ملی
شماره
TLpq303954938
زبان اثر
زبان متن نوشتاري يا گفتاري و مانند آن
انگلیسی
عنوان و نام پديدآور
عنوان اصلي
Pharmacokinetics of phenobarbital, carbamazepine, antipyrine, phenytoin, and protein binding of warfarin, phenytoin and propranolol in ducks, roosters and turkeys
نام عام مواد
[Thesis]
نام نخستين پديدآور
D. S. Tolbert
نام ساير پديدآوران
W. R. Ravis
وضعیت نشر و پخش و غیره
نام ناشر، پخش کننده و غيره
Auburn University
تاریخ نشرو بخش و غیره
1991
مشخصات ظاهری
نام خاص و کميت اثر
189
یادداشتهای مربوط به پایان نامه ها
جزئيات پايان نامه و نوع درجه آن
Ph.D.
کسي که مدرک را اعطا کرده
Auburn University
امتياز متن
1991
یادداشتهای مربوط به خلاصه یا چکیده
متن يادداشت
The pharmacokinetics of phenobarbital (PHB, 10 mg/kg), carbamazepine (CBZ, 7.5 mg/kg), and antipyrine (AP, 50 mg/kg) were studied in mature domestic turkeys, roosters, and ducks following a single IV administration. In addition, the bioavailability of PHB (11 mg/kg) was determined in turkeys as well as the pharmacokinetics of phenytoin (PHT) in male and female turkeys following single IV doses (5 and 15 mg/kg). The PHB clearance (Clt) for the rooster was similar to the Clt in the duck, but less than that observed for the turkey. Carbamazepine t1/2usd\betausd in the duck was significantly different from that observed in the rooster and turkey. The Clt of CBZ was significantly different for the duck as compared to the turkey and rooster. The Vmax of AP in the turkey was far greater than that observed for both duck and rooster. The t1/2usd\betausd and Clt were correspondingly different in turkeys when compared to duck and rooster. The Vd in male turkeys was 0.84 0.08 l/kg and 0.73 0.10 l/kg in females. The PHT Clt for female turkeys was two-fold greater than that observed for the males. The PHT t1/2usd\betausd for male and female turkeys were 1.85 0.54 and 2.20 1.01 hours, respectively. Percents bound propranolol at the low concentration in turkey, rooster, and duck were 90.0 4.37, 93.2 1.60, and 78.9 2.00%, respectively and for the high concentration were 89.5 3.80, 83.8 1.62, and 78.2 3.61%, respectively. Percents bound of phenytoin in the turkey, rooster, and duck with a low PHT concentration were 63.6 3.85, 64.6 4.61, and 60.5 8.36%, respectively and for the high concentration were 48.2 12.2, 40.0 12.8, and 50.3 + 8.95%, respectively. The percents bound warfarin in turkey, rooster, and duck plasma at the low concentration were 79.5 1.95, 89.0 1.80, and 73.4 3.17%, respectively and for the high concentration were 77.4 2.46, 80.0 2.96, and 66.6 6.91%, respectively. (Abstract shortened with permission of author.)
موضوع (اسم عام یاعبارت اسمی عام)
موضوع مستند نشده
Biological sciences
موضوع مستند نشده
Health and environmental sciences
موضوع مستند نشده
Pharmacology
موضوع مستند نشده
Veterinary services
موضوع مستند نشده
Veterinary services
نام شخص به منزله سر شناسه - (مسئولیت معنوی درجه اول )
مستند نام اشخاص تاييد نشده
D. S. Tolbert
مستند نام اشخاص تاييد نشده
W. R. Ravis
دسترسی و محل الکترونیکی
نام الکترونيکي
مطالعه متن کتاب وضعیت انتشار
فرمت انتشار
p
اطلاعات رکورد کتابشناسی
نوع ماده
[Thesis]
کد کاربرگه
276903
اطلاعات دسترسی رکورد
سطح دسترسي
a
تكميل شده
Y
