عنوان

Phytochemistry of Homalium zeylanicum (Flacourtiaceae) and Serjania salzmanniana (Sapindaceae)

شماره

TLpq304155183

زبان متن نوشتاري يا گفتاري و مانند آن

انگلیسی

عنوان اصلي

Phytochemistry of Homalium zeylanicum (Flacourtiaceae) and Serjania salzmanniana (Sapindaceae)

نام عام مواد

[Thesis]

نام نخستين پديدآور

O. A. Ekabo

نام ساير پديدآوران

N. R. Farnsworth

نام ناشر، پخش کننده و غيره

University of Illinois at Chicago, Health Sciences Center

تاریخ نشرو بخش و غیره

1994

نام خاص و کميت اثر

174

جزئيات پايان نامه و نوع درجه آن

Ph.D.

کسي که مدرک را اعطا کرده

University of Illinois at Chicago, Health Sciences Center

امتياز متن

1994

متن يادداشت

A phytochemical study of Homalium zeylanicum led to the isolation of eight novel and several known compounds. Salirepin, salireposide and the three related analogs, homaloside B, C and D are being reported as occurring in a species of the Flacourtiaceae for the first time. This group of phenolic glucosides is restricted to the Salicaceae (Order: Salicales) and may be considered a taxonomic marker for the family. Their presence in the Flacourtiaceae (Order: Violales) may have chemotaxonomic significance. The novel compounds from H. zeylanicum comprise an iridoid glucoside (6-O-(34usd \sp{\prime\prime}usd-dimethoxycinnamoyl)catalpol), a lignan (zeylanicin, (7-methoxy-8-hydroxydehydro-diconiferyl alcohol)), an acyclic ester(1-hydroxy-6-oxocyclohex-2-enoic acid methyl ester), a degraded carotenoid (3-hydroxy-usd\betausd-ionyl-usd\betausd- scD-glucopyranoside) and four benzenoid glycosides, homaloside A (1-O-benzyl-3-O-benzoyl-(usd\alphausd- scL-arabinopyranosy1-(1usd \tousd4)-usd\betausd- scD-glucopyranoside), homaloside B (1-(2-methoxybenzoyloxy) methyl-5-hydroxyphenyl-usd\betausd- scD-glucopyranoside), homaloside C (1-furoyloxymethyl-5-hydroxy phenyl-usd\betausd- scD-glucopyranoside) and homaloside D (1-(1-hydroxy-6-oxo-cyclohex-usd2usd -ene-carboxymethyl)-5-hydroxyphenyl-6-O-benzoyl-usd\betausd- scD-glucopyranoside). Four monodesmosidic saponins were obtained from Serjania salzmanniana and evaluated for molluscicidal action against Biomphalaria alexandrina, a vector of Schistosoma mansoni in the Nile Valley, Egypt. Two novel saponins named salzmannianoside A (3usd\betausd-hydroxy-23-formylolean-12-ene-28-oic acid 3-O- (usd\betausd- scD-glucopyranosyl-(1usd\tousd4)) - (usd\alphausd- scL-rhamnopyranosyl-(1usd\tousd2)) -usd\alphausd- scL-arabinopyranoside),salzmannianosideB(3usd \betausd,23-dihydroxyolean-usd1usd 2-ene-28-oic acid 3-O- (usd\betausd- scD-glucopyranosyl-(1usd\tousd4)) - (usd\alphausd- scL-arabinopyranosyl(1usd \tousd3)-usd\alphausd- scL-rhamnopyranosyl-(1usd \tousd2)) -usd\alphausd- scL-arabinopyranoside) usd\{usd69usd\}usd and the known saponins pulsatilla saponin D (3usd\betausd,23-dihydroxyolean-12-ene-28-oic acid-3-O- (usd\betausd- scD-glucopyranosyl-(1usd\tousd4)) - (usd\alphausd- scL-rhamnopyranosyl-(1usd\to usd2)) -usd\alphausd- scL-arabinopyranoside usd\{{\bf 67}\}usd and 3usd\betausd-hydroxyolean-12-ene-28-oic acid 3-O- (usd\betausd- scD-glucopyranosyl-(1usd\to usd4)) usd\alphausd- scL-rhamnopyranosyl-(1usd \tousd2)) -usd\alphausd- scL-arabinopyranoside were isolated from this plant. All the saponins were molluscicidal, causing greater than 90% kill at a concentration of 10 ppm except for salzmannianoside B which caused only a 70% mortality at 20 ppm. All the structures were solved by 1D and 2D nmr spectroscopy in combination with the other spectral (ms, ir, uv) and chemical techniques.

موضوع مستند نشده

Health and environmental sciences

موضوع مستند نشده

Pharmaceuticals

موضوع مستند نشده

Pharmaceuticals

موضوع مستند نشده

Pharmacology

موضوع مستند نشده

Pure sciences

مستند نام اشخاص تاييد نشده

N. R. Farnsworth

مستند نام اشخاص تاييد نشده

O. A. Ekabo

نام الکترونيکي

فرمت انتشار

p

نوع ماده

[Thesis]

کد کاربرگه

276903

سطح دسترسي

a

تكميل شده

Y