عنوان
پدید آورنده
موضوع
رده
کتابخانه
محل استقرار
TL48666
انگلیسی
Biosynthesis and cellular actions of bioactive natural products
[Thesis]
Shogo Mori
Watanabe, Coran M. H.
Texas A&M University
2015
193
Committee members: Barondeau, David P.; Begley, Tadhg P.; Reinhart, Gregory D.
Place of publication: United States, Ann Arbor; ISBN=978-1-339-52557-0
Ph.D.
Chemistry
Texas A&M University
2015
The utilization of natural products as therapeutic agents has been an invaluable resource throughout medicinal history. Through the combined application of combinatorial biosynthesis, the modification of a natural product by engineered enzymes, and the isolation of new bioactive natural products, the discovery of new therapeutic agents may be achieved. This work shows the novel enzymatic interaction in the biosynthesis of a known therapeutic agent and the isolation of a new bioactive natural product.
Biochemistry
Pure sciences;Cyanobacteria;Macrolactone;Natural product;Nonribosomal peptide synthetase;Polyketide;Polyketide synthase;Streptomyces;Thioesterase
Al-Kamal, Sohaib Kamal Mahmood
Watanabe, Coran M. H.
Chemistry
Texas A&M University
1771836288; 10026829
مطالعه متن کتاب p
[Thesis]
276903
a
Y
